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Mystery Behind Neuron Death in Alzheimer’s Decoded

Researchers have unveiled the mystery behind neuron death in Alzheimer’s disease. A groundbreaking study reveals that neurons undergo a programmed cell death, necroptosis, when exposed to amyloid plaques and tau tangles, hallmark proteins linked to Alzheimer’s.

Neuronal cell loss is a defining feature of Alzheimer’s disease (AD), but the underlying mechanisms remain unclear. We xenografted human or mouse neurons into the brain of a mouse model of AD.

More importantly, the research team was able to prevent the death of neurons, rescuing them in the process. The discovery opens new pathways for potential future treatments

 

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