Researchers stimulate areas vital to consciousness in monkeys' brains -- and it wakes them up

One of the central questions in neuroscience is clarifying where in the brain consciousness, which is the ability to experience internal and external sensations, arises. On February 12 in the journal Neuron, researchers report that a specific area in the brain, the central lateral thalamus, appears to play a key role. In monkeys under anesthesia, stimulating this area was enough to wake the animals and elicit normal waking behaviors.

Previous studies, including EEG and fMRI studies in humans, had suggested that certain areas of the brain, including the parietal cortex and the thalamus, appear to be involved in consciousness. "We decided to go beyond the classical approach of recording from one area at a time," says senior author Yuri Saalmann, an assistant professor at the University of Wisconsin, Madison. "We recorded from multiple areas at the same time to see how the entire network behaves."

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