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Researchers map how Alzheimer’s pathology spreads across brain networks

Capitalizing on recent advances in neuroimaging and genetic biomarker research, scientists have been able to identify specific pathways by...

Capitalizing on recent advances in neuroimaging and genetic biomarker research, scientists have been able to identify specific pathways by which tau and beta-amyloid, two proteins that are hallmarks of Alzheimer’s disease, accumulate in the brain over time. The NIA-supported researchers also found that the patterns of tau and beta-amyloid accumulation were related to specific genetic profiles, providing better understanding of Alzheimer’s disease risk and possible new avenues for diagnosis and monitoring of the disease.

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