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Poor neuronal connectivity between two brain regions may be predictive of Alzheimer's risk

Late-onset Alzheimer's disease (LOAD), the one that appears after age 65, is the most common form of this neurodegenerative disease and accounts for more than 90% of cases.

Late-onset Alzheimer's disease (LOAD), the one that appears after age 65, is the most common form of this neurodegenerative disease and accounts for more than 90% of cases. The first brain changes associated with the disease may appear years before the first symptoms, but the lack of clear risk markers complicates the application of the appropriate prevention strategies for those that are more vulnerable.

Now a study, published in the Journal of Psychiatric Research, has provided the first evidence that a poor neuronal connection between the brainstem and cerebellum may be predictive of the risk of developing Alzheimer's. The article has the participation of researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the CIBER of Mental Health (CIBERSAM), Barcelona University and Bellvitge University Hospital, in collaboration with researchers from the FLENI center of Buenos Aires (Argentina) and the CIBER of Neurodegenerative Diseases (CIBERNED)…

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