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Processing of structural images

There are several metrics that one can use to test a morphometry-related hypothesis such as gray matter volume, white matter volume, cortical thickness, or cortical curvature. This talk will describe two techniques for analyzing brain morphometry: voxel-based morphometry (VBM) and surface-based analysis (SBA).

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This kind of data is analyzed using SMP (SPM12), CAT 12 or Freesurfer (ROI analysis and vertex wise analysis (by FSGD or QDEC)). These analyses are included Voxel-based morphometry, Deformation-based morphometry, Region-based morphometry and Surface-based morphometry.

An example of parcellated image

Figure 1: An example of parcellated image

An example of VBM analysis.

Figure 2: An example of VBM analysis.

An example of SBM analysis.

Figure 3: An example of SBM analysis.

One of the important steps in preprocessing in Freesurfer that we do is quality control and manually change certain files created during the recon-all processing stream and then regenerate the surfaces.

An example of manually correcting.

Figure 4: An example of manually correcting.

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