The Signs of Schizophrenia in the Sleeping Brain
An international team of researchers, including HSE Univesrity's Sofya Kulikova, have discovered clues to why electroencephalograms (EEG) of people with schizophrenic show a deficit of sleep spindles. The article was published in the journal Schizophrenia Research on June 5.
Individuals with schizophrenia are often characterized by a deficit of sleep spindles--specific bursts in the brain's electrical activity that can be recorded by EEG while the patient is sleeping. Such a disorder is also observed in patients with other psychoses or predisposition to them.
Sleep spindles are generated by the thalamic reticular nucleus. Thalamus is a brain region that redistributes sensory information from sensory organs to other regions, and its reticular nucleus is involved in regulating the nervous system's activity. In particular, the reticular nucleus helps to filter the information exchanged by the thalamus and the cortex.
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